I got my first-hand look Tuesday along First Avenue: for the several minutes or so walking South along 1st it looked as if most vehicles were respecting the new bus, bike and parking lanes. But only time (and NYPD enforcement or mockery of) will tell.
Update 7/21/10: The problem with the Second avenue bus lane is that is adjacent to the curb, which means that trucks park there to load/unload. This is a clear difference from 1st Ave, where the bus lane is adjacent to a parking lane.
Here's some pics!
Clear view of new bike lanes at 1st and E 9th (looking South):

DOT Contractors painting bus lane along 1st Avenue:


DOT Contractors installing pedestrian refuge island at 1st and Houston:

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